output
20202026
most citedSARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways

2.7k citations

18 papers

cs.LG2026

Causal Machine Learning Is Not a Panacea: A Roadmap for Observational Causal Inference in Health

Donna Tjandra, Trenton Chang, Sonali Parbhoo +8

Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal…

q-bio.GN2025

Combining multiplexed functional data to improve variant classification

Atlas of Variant Effects Alliance, :, Jeffrey D. Calhoun +10

With the surge in the number of variants of uncertain significance (VUS) reported in ClinVar in recent years, there is an imperative to resolve VUS at scale. Multiplexed assays of…

q-bio.NC2025★ 119 cited

KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation

L Cif, D Demailly, JP Lin +112

Heterozygous mutations in KMT2B are associated with an early-onset, progressive, and often complex dystonia (DYT28). Key characteristics of typical disease include focal motor feat…

cs.AI2024★ 19 cited

PadChest-GR: A Bilingual Chest X-ray Dataset for Grounded Radiology Report Generation

Daniel C. Castro, Aurelia Bustos, Shruthi Bannur +11

Radiology report generation (RRG) aims to create free-text radiology reports from clinical imaging. Grounded radiology report generation (GRRG) extends RRG by including the localis…

eess.IV2024★ 4 cited

Parameter choices in HaarPSI for IQA with medical images

Clemens Karner, Janek Gröhl, Ian Selby +11

When developing machine learning models, image quality assessment (IQA) measures are a crucial component for the evaluation of obtained output images. However, commonly used full-r…

eess.IV2024★ 6 cited

A study on the adequacy of common IQA measures for medical images

Anna Breger, Clemens Karner, Ian Selby +11

Image quality assessment (IQA) is standard practice in the development stage of novel machine learning algorithms that operate on images. The most commonly used IQA measures have b…

cs.HC2024★ 78 cited

Multimodal Healthcare AI: Identifying and Designing Clinically Relevant Vision-Language Applications for Radiology

Nur Yildirim, Hannah Richardson, Maria T. Wetscherek +18

Recent advances in AI combine large language models (LLMs) with vision encoders that bring forward unprecedented technical capabilities to leverage for a wide range of healthcare a…

stat.AP2024

The NOSTRA model: coherent estimation of infection sources in the case of possible nosocomial transmission

David J Pascall, Chris Jackson, Stephanie Evans +8

Nosocomial infections have important consequences for patients and hospital staff: they worsen patient outcomes and their management stresses already overburdened health systems. A…

cs.CV2024★ 69 cited

Exploring scalable medical image encoders beyond text supervision

Fernando Pérez-García, Harshita Sharma, Sam Bond-Taylor +12

Language-supervised pre-training has proven to be a valuable method for extracting semantically meaningful features from images, serving as a foundational element in multimodal sys…

cs.AI2023★ 5 cited

Going faster to see further: GPU-accelerated value iteration and simulation for perishable inventory control using JAX

Joseph Farrington, Kezhi Li, Wai Keong Wong +1

Value iteration can find the optimal replenishment policy for a perishable inventory problem, but is computationally demanding due to the large state spaces that are required to re…

stat.ME2023★ 9 cited

Sample size determination via learning-type curves

Alimu Dayimu, Nikola Simidjievski, Nikolaos Demiris +1

This paper is concerned with sample size determination methodology for prediction models. We propose combining the individual calculations via a learning-type curve. We suggest two…

cs.SE2022★ 11 cited

Navigating the challenges in creating complex data systems: a development philosophy

Sören Dittmer, Michael Roberts, Julian Gilbey +6

In this perspective, we argue that despite the democratization of powerful tools for data science and machine learning over the last decade, developing the code for a trustworthy a…

cs.LG2022★ 131 cited

Classification of datasets with imputed missing values: does imputation quality matter?

Tolou Shadbahr, Michael Roberts, Jan Stanczuk +15

Classifying samples in incomplete datasets is a common aim for machine learning practitioners, but is non-trivial. Missing data is found in most real-world datasets and these missi…

cs.CV2021

Transductive image segmentation: Self-training and effect of uncertainty estimation

Konstantinos Kamnitsas, Stefan Winzeck, Evgenios N. Kornaropoulos +9

Semi-supervised learning (SSL) uses unlabeled data during training to learn better models. Previous studies on SSL for medical image segmentation focused mostly on improving model…

q-bio.QM2021★ 2 cited

Machine Learning and Glioblastoma: Treatment Response Monitoring Biomarkers in 2021

Thomas Booth, Bernice Akpinar, Andrei Roman +10

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed…

astro-ph.HE2020★ 10 cited

Population Properties of Compact Objects from the Second LIGO-Virgo Gravitational-Wave Transient Catalog

The LIGO Scientific Collaboration, the Virgo Collaboration, R. Abbott +1338

We report on the population of the 47 compact binary mergers detected with a false-alarm rate 1/yr in the second LIGO--Virgo Gravitational-Wave Transient Catalog, GWTC-2. We observ…

cs.LG2020★ 1k cited

Common pitfalls and recommendations for using machine learning to detect and prognosticate for COVID-19 using chest radiographs and CT scans

Michael Roberts, Derek Driggs, Matthew Thorpe +13

Machine learning methods offer great promise for fast and accurate detection and prognostication of COVID-19 from standard-of-care chest radiographs (CXR) and computed tomography (…

q-bio.CB2020★ 2.7k cited

SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways

Waradon Sungnak, Ni Huang, Christophe Bécavin +2

The SARS-CoV-2 coronavirus, the etiologic agent responsible for COVID-19 coronavirus disease, is a global threat. To better understand viral tropism, we assessed the RNA expression…