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4 papers · 1 filter
Spatial measures of genetic heterogeneity during carcinogenesis
K. Storey, M. D. Ryser, K. Leder +1
In this work we explore the temporal dynamics of spatial heterogeneity during the process of tumorigenesis from healthy tissue. We utilize a spatial stochastic process model of mut…
Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
Peter Hraber, Bette Korber, Kshitij Wagh +16
Within-host genetic sequencing from samples collected over time provides a dynamic view of how viruses evade host immunity. Immune-driven mutations might stimulate neutralization b…
Fused Analytical and Iterative Reconstruction (AIR) via modified proximal forward-backward splitting: a FDK-based iterative image reconstruction example for CBCT
Hao Gao
This work is to develop a general framework, namely analytical iterative reconstruction (AIR) method, to incorporate analytical reconstruction (AR) method into iterative reconstruc…
Detecting somatic mutations in genomic sequences by means of Kolmogorov-Arnold analysis
V. G. Gurzadyan, H. Yan, G. Vlahovic +7
The Kolmogorov-Arnold stochasticity parameter technique is applied for the first time to the study of cancer genome sequencing, to reveal mutations. Using data generated by next ge…