105 citations
2 papers
q-bio.CB2005
The Effects of EGF-Receptor Density on Multiscale Tumor Growth Patterns
Chaitanya A. Athale, Thomas S. Deisboeck
We studied the effects of epidermal growth factor receptor (EGFR) density on tumor growth dynamics, both on the sub- and the multi-cellular level using our previously developed mod…
q-bio.CB2004★ 105 cited
Simulating the Impact of a Molecular 'Decision-Process' on Cellular Phenotype and Multicellular Patterns in Brain Tumors
Chaitanya Athale, Yuri Mansury, Thomas S. Deisboeck
Experimental evidence indicates that human brain cancer cells proliferate or migrate, yet do not display both phenotypes at the same time. Here, we present a novel computational mo…