222 citations
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5 papers · 1 filter
Single molecule enzymology a la Michaelis-Menten
Ramon Grima, Nils Walter, Santiago Schnell
In the past one hundred years, deterministic rate equations have been successfully used to infer enzyme-catalysed reaction mechanisms and to estimate rate constants from reaction k…
HINO: a BFO-aligned ontology representing human molecular interactions and pathways
Yongqun He, Zoushuang Xiang
Many database resources, such as Reactome, collect manually annotated reactions, interactions, and pathways from peer-reviewed publications. The interactors (e.g., a protein), inte…
Disease Prediction based on Functional Connectomes using a Scalable and Spatially-Informed Support Vector Machine
Takanori Watanabe, Daniel Kessler, Clayton Scott +2
Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to…
Structure and Dynamics of Coauthorship, Citation, and Impact within CSCW
Brian Keegan, Dan Horn, Thomas A. Finholt +1
CSCW has stabilized as an interdisciplinary venue for computer, information, cognitive, and social scientists but has also undergone significant changes in its format in recent yea…
Meta-Analysis of Gene Level Association Tests
Dajiang J. Liu, Gina M. Peloso, Xiaowei Zhan +18
The vast majority of connections between complex disease and common genetic variants were identified through meta-analysis, a powerful approach that enables large samples sizes whi…