282 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- ETH ZurichCH12 papers
- Centre National de la Recherche ScientifiqueFR5 papers
- Columbia UniversityUS2 papers
- École Normale Supérieure - PSLFR2 papers
- Harvard UniversityUS2 papers
- Imperial College LondonGB2 papers
- Institut national de recherche en sciences et technologies du numériqueFR2 papers
- Laboratoire de Probabilités et Modèles AléatoiresFR2 papers
- Lyon 1 UniversitéFR2 papers
- University College LondonGB2 papers
- University of Hawaiʻi at MānoaUS2 papers
- University of OxfordGB2 papers
12 papers
From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics
Susanna Manrubia, José A. Cuesta, Jacobo Aguirre +15
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution. We refer to t…
The Surprising Creativity of Digital Evolution: A Collection of Anecdotes from the Evolutionary Computation and Artificial Life Research Communities
Joel Lehman, Jeff Clune, Dusan Misevic +50
Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic pr…
Detecting the Collapse of Cooperation in Evolving Networks
Matteo Cavaliere, Guoli Yang, Vincent Danos +1
The sustainability of structured biological, social, economic and ecological communities are often determined by the outcome of social conflicts between cooperative and selfish ind…
Recovering a stochastic process from noisy ensembles of many single particle trajectories
Nathanael Hoze, David Holcman
Recovering a stochastic process from noisy ensembles of single particle trajectories (SPTs) is resolved here using the Langevin equation as a model. The massive redundancy containe…
Spatial heterogeneity in drug concentrations can facilitate the emergence of resistance to cancer therapy
Feng Fu, Martin A. Nowak, Sebastian Bonhoeffer
Acquired resistance is one of the major barriers to successful cancer therapy. The development of resistance is commonly attributed to genetic heterogeneity. However, heterogeneity…
Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1
Alison L. Hill, Daniel I. S. Rosenbloom, Feng Fu +2
Massive research efforts are now underway to develop a cure for HIV infection, allowing patients to discontinue lifelong combination antiretroviral therapy (ART). New latency-rever…
Evolutionary Game Dynamics in Populations with Heterogeneous Structures
Wes Maciejewski, Feng Fu, Christoph Hauert
Evolutionary graph theory is a well established framework for modelling the evolution of social behaviours in structured populations. An emerging consensus in this field is that gr…
Macro-evolutionary models and coalescent point processes: The shape and probability of reconstructed phylogenies
Amaury Lambert, Tanja Stadler
Forward-time models of diversification (i.e., speciation and extinction) produce phylogenetic trees that grow "vertically" as time goes by. Pruning the extinct lineages out of such…
Phylogenetic analysis accounting for age-dependent death and sampling with applications to epidemics
Amaury Lambert, Helen K. Alexander, Tanja Stadler
The reconstruction of phylogenetic trees based on viral genetic sequence data sequentially sampled from an epidemic provides estimates of the past transmission dynamics, by fitting…
Can high risk fungicides be used in mixtures without selecting for fungicide resistance?
Alexey Mikaberidze, Bruce A. McDonald, Sebastian Bonhoeffer
Fungicide mixtures produced by the agrochemical industry often contain low-risk fungicides, to which fungal pathogens are fully sensitive, together with high-risk fungicides known…
Pathogen evolution in switching environments: a hybrid dynamical system approach
Jozsef Z. Farkas, Peter Hinow, Jan Engelstädter
We propose a hybrid dynamical system approach to model the evolution of a pathogen that experiences different selective pressures according to a stochastic process. In every enviro…
Mod/Resc Parsimony Inference
Igor Nor, Danny Hermelin, Sylvain Charlat +4
We address in this paper a new computational biology problem that aims at understanding a mechanism that could potentially be used to genetically manipulate natural insect populati…