Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning

Philippe Rondard, Siluo Huang, Carine Monnier +9

The G-protein-coupled receptor (GPCR) activated by the neurotransmitter GABA is made up of two subunits, GABA(B1) and GABA(B2). GABA(B1) binds agonists, whereas GABA(B2) is require…