81 citations
2 papers
q-bio.BM2008★ 81 cited
Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit
Jianfeng Liu, Damien Maurel, Sébastien Etzol +4
The gamma-aminobutyric acid type B (GABAB) receptor is an allosteric complex made of two subunits, GABAB1 (GB1) and GABAB2 (GB2). Both subunits are composed of an extracellular Ven…
q-bio.NC2008★ 80 cited
Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning
Philippe Rondard, Siluo Huang, Carine Monnier +9
The G-protein-coupled receptor (GPCR) activated by the neurotransmitter GABA is made up of two subunits, GABA(B1) and GABA(B2). GABA(B1) binds agonists, whereas GABA(B2) is require…