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20212025
most citedEnzyme-enriched condensates show self-propulsion, positioning, and coexistence

59 citations

Showing physics.bio-phShow all

8 papers · 1 filter

physics.bio-ph2025★ 1 cited

Delay-facilitated self-assembly in compartmentalized systems

Severin Angerpointner, Richard Swiderski, Erwin Frey

Self-assembly processes in biological and synthetic biomolecular systems are often governed by the spatial separation of biochemical processes. While previous work has focused on o…

physics.bio-ph2024★ 3 cited

Cell bulging and extrusion in a three-dimensional bubbly vertex model for curved epithelial sheets

Oliver M. Drozdowski, Büşra Kocameşe, Kim E. Boonekamp +2

Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve compl…

physics.bio-ph2024

Self-organized homogenization of flow networks

Julien Bouvard, Swarnavo Basu, Charlott Leu +4

From the vasculature of animals to the porous media making up batteries, the core task of flow networks is to transport solutes and perfuse all cells or media equally with resource…

physics.bio-ph2024★ 11 cited

Morphological instability at topological defects in a three-dimensional vertex model for spherical epithelia

Oliver M. Drozdowski, Ulrich S. Schwarz

Epithelial monolayers are a central building block of complex organisms. Topological defects have emerged as important elements for single cell behavior in flat epithelia. Here we…

physics.bio-ph2023★ 59 cited

Enzyme-enriched condensates show self-propulsion, positioning, and coexistence

Leonardo Demarchi, Andriy Goychuk, Ivan Maryshev +1

Enzyme-enriched condensates can organize the spatial distribution of their substrates by catalyzing non-equilibrium reactions. Conversely, an inhomogeneous substrate distribution i…

physics.bio-ph2021★ 45 cited

Bridging scales in a multiscale pattern-forming system

Laeschkir Würthner, Fridtjof Brauns, Grzegorz Pawlik +4

Self-organized pattern formation is vital for many biological processes. Reaction-diffusion models have advanced our understanding of how biological systems develop spatial structu…

physics.bio-ph2021★ 2 cited

Length Regulation Drives Self-Organization in Filament-Motor Mixtures

Moritz Striebel, Fridtjof Brauns, Erwin Frey

Cytoskeletal networks form complex intracellular structures. Here we investigate a minimal model for filament-motor mixtures in which motors act as depolymerases and thereby regula…

physics.bio-ph2021★ 40 cited

Dynamic Actuation of DNA-Assembled Plasmonic Nanostructures in Microfluidic Cell-Sized Compartments

Kerstin Goepfrich, Maximilian J. Urban, Christoph Frey +3

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale mo…