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- Lawrence Berkeley National LaboratoryUS198 papers
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- Institut National de Physique Nucléaire et de Physique des ParticulesFR159 papers
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21 papers · 1 filter
Signaling Network Assessment of Mutations and Copy Number Variations Predicts Breast Cancer Subtype-specific Drug Targets
Naif Zaman, Lei Li, Maria Jaramillo +9
Individual cancer cells carry a bewildering number of distinct genomic alterations i.e., copy number variations and mutations, making it a challenge to uncover genomic-driven mecha…
Resonances and convex co-compact congruence subgroups of PSL2(Z)
Frédéric Naud, Dmitry Jakobson
This papers deals with congruence subgroups of convex cocompact subgroups of PSL2(Z). We examine the behaviour of the resonance spectrum when the congruence parameter q goes to inf…
Metamodelling: State of the Art and Research Challenges
Jonathan Sprinkle, Bernhard Rumpe, Hans Vangheluwe +1
This chapter discusses the current state of the art, and emerging research challenges, for metamodelling. In the state-of-the-art review on metamodelling, we review approaches, abs…
On a Generalized Entropy Measure Leading to the Pathway Model: with a preliminary application to solar neutrino data
A. M. Mathai, H. J. Haubold
An entropy for the scalar variable case, parallel to Havrda-Charvat entropy was introduced by the first author and the properties and its connection to Tsallis non-extensive statis…
Cancer systems biology in the genome sequencing era: Part 2, evolutionary dynamics of tumor clonal networks and drug resistance
Edwin Wang, Jinfeng Zou, Naif Zaman +3
A tumor often consists of multiple cell subpopulations (clones). Current chemo-treatments often target one clone of a tumor. Although the drug kills that clone, other clones overta…
Cancer systems biology in the genome sequencing era: Part 1, dissecting and modeling of tumor clones and their networks
Edwin Wang, Jinfeng Zou, Naif Zaman +3
Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation…