472 citations
- Friedrich Schiller University JenaDE19 papers
- Centre National de la Recherche ScientifiqueFR7 papers
- ETH ZurichCH7 papers
- Johannes Gutenberg University MainzDE7 papers
- Institut National de Physique Nucléaire et de Physique des ParticulesFR6 papers
- Jagiellonian UniversityPL6 papers
- KU LeuvenBE6 papers
- Laboratoire de Physique Corpusculaire de CaenFR6 papers
- Leibniz Institute of Photonic TechnologyDE6 papers
- Paul Scherrer InstituteCH6 papers
- Université Grenoble AlpesFR6 papers
- Université Paris-SudFR6 papers
11 papers · 1 filter
Fast ATP-dependent Subunit Rotation in Reconstituted FoF1-ATP Synthase Trapped in Solution
Thomas Heitkamp, Michael Börsch
FoF1-ATP synthases are ubiquitous membrane-bound, rotary motor enzymes that can catalyze ATP synthesis and hydrolysis. Their enzyme kinetics are controlled by internal subunit rota…
Observing monomer - dimer transitions of neurotensin receptors 1 in single SMALPs by homoFRET and in an ABELtrap
André Dathe, Thomas Heitkamp, Iván Pérez +5
G protein-coupled receptors (GPCRs) are a large superfamily of membrane proteins that are activated by extracellular small molecules or photons. Neurotensin receptor 1 (NTSR1) is a…
Ligand-induced oligomerization of the human GPCR neurotensin receptor 1 monitored in living HEK293T cells
Anika Westphal, Hendrik Sielaff, Stefanie Reuter +3
The human neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that can be expressed in HEK293T cells by stable transfection. Its ligand is a 13-amino-acid peptide that b…
Binding of the immunomodulatory drug Bz-423 to mitochondrial FoF1-ATP synthase in living cells by FRET acceptor photobleaching
Ilka Starke, Kathryn M. Johnson, Jan Petersen +4
Bz-423 is a promising new drug for treatment of autoimmune diseases. This small molecule binds to subunit OSCP of the mitochondrial enzyme FoF1-ATP synthase and modulates its catal…
Observing single FoF1-ATP synthase at work using an improved fluorescent protein mNeonGreen as FRET donor
Thomas Heitkamp, Gabriele Deckers-Hebestreit, Michael Börsch
Adenosine triphosphate (ATP) is the universal chemical energy currency for cellular activities provided mainly by the membrane enzyme FoF1-ATP synthase in bacteria, chloroplasts an…
3D-localization microscopy and tracking of FoF1-ATP synthases in living bacteria
Anja Renz, Marc Renz, Diana Kluetsch +2
FoF1-ATP synthases are membrane-embedded protein machines that catalyze the synthesis of adenosine triphosphate. Using photoactivation-based localization microscopy (PALM) in TIR-i…