14 citations · 23 across the 6 of their papers we have counts for
7 papers
Fast ATP-dependent Subunit Rotation in Reconstituted FoF1-ATP Synthase Trapped in Solution
Thomas Heitkamp, Michael Börsch
FoF1-ATP synthases are ubiquitous membrane-bound, rotary motor enzymes that can catalyze ATP synthesis and hydrolysis. Their enzyme kinetics are controlled by internal subunit rota…
Observing monomer - dimer transitions of neurotensin receptors 1 in single SMALPs by homoFRET and in an ABELtrap
André Dathe, Thomas Heitkamp, Iván Pérez +5
G protein-coupled receptors (GPCRs) are a large superfamily of membrane proteins that are activated by extracellular small molecules or photons. Neurotensin receptor 1 (NTSR1) is a…
Ligand-induced oligomerization of the human GPCR neurotensin receptor 1 monitored in living HEK293T cells
Anika Westphal, Hendrik Sielaff, Stefanie Reuter +3
The human neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that can be expressed in HEK293T cells by stable transfection. Its ligand is a 13-amino-acid peptide that b…
Towards monitoring conformational changes of the GPCR neurotensin receptor 1 by single-molecule FRET
Thomas Heitkamp, Reinhard Grisshammer, Michael Börsch
Neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that is important for signaling in the brain and the gut. Its agonist ligand neurotensin (NTS), a 13-amino-acid pepti…
Imaging cytochrome C oxidase and FoF1-ATP synthase in mitochondrial cristae of living human cells by FLIM and superresolution microscopy
Franziska Foertsch, Mykhailo Ilchenko, Thomas Heitkamp +6
Cytochrome C oxidase and FoF1-ATP synthase constitute complex IV and V, respectively, of the five membrane-bound enzymes in mitochondria comprising the respiratory chain. These enz…
Observing conformations of single FoF1-ATP synthases in a fast anti-Brownian electrokinetic trap
Bertram Su, Monika G. Dueser, Nawid Zarrabi +3
To monitor conformational changes of individual membrane transporters in liposomes in real time, we attach two fluorophores to selected domains of a protein. Sequential distance ch…