33 citations · 242 across the 33 of their papers we have counts for
33 papers
Multichannel-GaAsP-photomultiplier-based fiber bundle ISM-STED microscope
Marcus Babin, Simone Fabian, Michael Reibe +3
The usage of a GaAsP (gallium arsenide phosphide) photomultiplier for microscopical imaging allows the evaluation of low-light luminescent objects. We designed a setup for collecti…
Single NV in nanodiamond for quantum sensing of protein dynamics in an ABEL trap
Ivan Perez, Anke Krueger, Joerg Wrachtrup +2
Enzymes are cellular protein machines using a variety of conformational changes to power fast biochemical catalysis. Our goal is to exploit the single-spin properties of the lumine…
Monitoring oligomerization dynamics of individual human neurotensin receptors 1 in living cells and in SMALP nanodiscs
Lukas Spantzel, Iván Pérez, Thomas Heitkamp +4
The human neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor. The receptor is activated by a small peptide ligand neurotensin. NTSR1 can be expressed in HEK cells by st…
Ligand-induced oligomerization of the human GPCR neurotensin receptor 1 monitored in living HEK293T cells
Anika Westphal, Hendrik Sielaff, Stefanie Reuter +3
The human neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that can be expressed in HEK293T cells by stable transfection. Its ligand is a 13-amino-acid peptide that b…
Visualizing mitochondrial FoF1-ATP synthase as the target of the immunomodulatory drug Bz-423
Ilka Starke, Gary D. Glick, Michael Börsch
Targeting the mitochondrial enzyme FoF1-ATP synthase and modulating its catalytic activities with small molecules is a promising new approach for treatment of autoimmune diseases.…
Towards monitoring conformational changes of the GPCR neurotensin receptor 1 by single-molecule FRET
Thomas Heitkamp, Reinhard Grisshammer, Michael Börsch
Neurotensin receptor 1 (NTSR1) is a G protein-coupled receptor that is important for signaling in the brain and the gut. Its agonist ligand neurotensin (NTS), a 13-amino-acid pepti…