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Correlated connectivity and the distribution of firing rates in the neocortex
Alexei Koulakov, Tomas Hromadka, Anthony M. Zador
Two recent experimental observations pose a challenge to many cortical models. First, the activity in the auditory cortex is sparse, and firing rates can be described by a lognorma…
Optimal axonal and dendritic branching strategies during the development of neural circuitry
Dmitry Tsigankov, Alexei Koulakov
In developing brain, axons and dendrites are capable of connecting to each other with high precision. Recent advances in imaging have allowed for the monitoring of axonal, dendriti…
Sperry versus Hebb: Topographic mapping in Isl2/EphA3 mutant mice
Dmitry Tsigankov, Alexei Koulakov
In wild-type mice axons of retinal ganglion cells establish topographically precise projection to the superior colliculus of the midbrain. This implies that axons of neighboring re…
Neural integrator - a sandpile model
Maxim Nikitchenko, Alexei Koulakov
We investigated a model for the neural integrator based on hysteretic units connected by positive feedback. Hysteresis is assumed to emerge from the intrinsic properties of the cel…