activity
20012025
most citedEquitability, mutual information, and the maximal information coefficient

691 citations · 1k across the 11 of their papers we have counts for

collaborators

13 papers

cs.LG2025

Flash Invariant Point Attention

Andrew Liu, Axel Elaldi, Nicholas T Franklin +4

Invariant Point Attention (IPA) is a key algorithm for geometry-aware modeling in structural biology, central to many protein and RNA models. However, its quadratic complexity limi…

physics.bio-ph2019

Physics Approaches to the Spatial Distribution of Immune Cells in Tumors

Clare C. Yu, Juliana C. Wortman, Ting-Fang He +12

The goal of immunotherapy is to enhance the ability of the immune system to kill cancer cells. Immunotherapy is more effective and, in general, the prognosis is better, when more i…

q-bio.QM2015★ 35 cited

Learning quantitative sequence-function relationships from massively parallel experiments

Gurinder S. Atwal, Justin B. Kinney

A fundamental aspect of biological information processing is the ubiquity of sequence-function relationships -- functions that map the sequence of DNA, RNA, or protein to a biochem…

q-bio.QM2013★ 691 cited

Equitability, mutual information, and the maximal information coefficient

Justin B. Kinney, Gurinder S. Atwal

Reshef et al. recently proposed a new statistical measure, the "maximal information coefficient" (MIC), for quantifying arbitrary dependencies between pairs of stochastic quantitie…

q-bio.GN2013

Kerfuffle: a web tool for multi-species gene colocalization analysis

Robert Aboukhalil, Bernard Fendler, Gurinder S. Atwal

The evolutionary pressures that underlie the large-scale functional organization of the genome are not well understood in eukaryotes. Recent evidence suggests that functionally sim…

q-bio.GN2012★ 2 cited

Utilizing RNA-Seq Data for Cancer Network Inference

Ying Cai, Bernard Fendler, Gurinder S. Atwal

An important challenge in cancer systems biology is to uncover the complex network of interactions between genes (tumor suppressor genes and oncogenes) implicated in cancer. Next g…