output
20212025
most citedDoes FLASH deplete Oxygen? Experimental Evaluation for Photons, Protons and Carbon Ions

169 citations

13 papers

physics.med-ph2025

Clinical beam test of inter- and intra-fraction relative range monitoring in carbon ion radiotherapy

Devin Hymers, Sebastian Schroeder, Olga Bertini +5

Interaction Vertex Imaging (IVI) is used for range monitoring (RM) in carbon ion radiotherapy. The purpose of RM is to measure the Bragg peak (BP) position for each contributing be…

physics.med-ph2025

Direct optimization of the probability of lesion origin in proton treatment planning for low-grade glioma patients

Tim Ortkamp, Habiba Sallem, Semi Harrabi +4

In proton therapy of low-grade glioma (LGG) patients, contrast-enhancing brain lesions (CEBLs) on magnetic resonance imaging are considered predictive of late radiation-induced les…

physics.med-ph2025

An ion treatment planning framework for inclusion of nanodosimetric ionization detail through cluster dose

Simona Facchiano, Ramon Ortiz, Remo Cristoforetti +4

Nanodosimetry relates Ionization Detail (ID) and ionization parameters (Ip) to biological endpoints relevant for charged-particle radiotherapy. This supports a more physics-based m…

physics.med-ph2025

Helium Range Viability for Online Range Probing in Mixed Carbon-Helium Beams

Jennifer J. Hardt, Alexander A. Pryanichnikov, Oliver Jäkel +2

Background: Recently, mixed carbon-helium beams were proposed for range verification in carbon ion therapy: Helium, with three times the range of carbon, serves as an on-line range…

physics.acc-ph2025★ 1 cited

Knock Out Slow Extraction Using Betatron Sidebands at High Harmonics

Philipp Niedermayer, Rahul Singh, Eike Feldmeier +2

Radio frequency knock out resonant slow extraction is a standard method for extracting stored particle beams from synchrotrons by transverse excitation. Excitation signals comprisi…

physics.med-ph2025★ 19 cited

SynthRAD2025 Grand Challenge dataset: generating synthetic CTs for radiotherapy

Adrian Thummerer, Erik van der Bijl, Arthur Jr Galapon +16

Medical imaging is essential in modern radiotherapy, supporting diagnosis, treatment planning, and monitoring. Synthetic imaging, particularly synthetic computed tomography (sCT),…