3 papers
physics.med-ph2025
LET-modifying joint optimization for mixed-modality photon-proton treatment planning
Lisa Seckler, Amit Ben Antony Bennan, Niklas Wahl
As depth increases, linear energy transfer (LET) rises toward the distal edge of the Bragg peak, boosting the radiobiological effectiveness (RBE). To manage the biological variatio…
physics.med-ph2025
An ion treatment planning framework for inclusion of nanodosimetric ionization detail through cluster dose
Simona Facchiano, Ramon Ortiz, Remo Cristoforetti +4
Nanodosimetry relates Ionization Detail (ID) and ionization parameters (Ip) to biological endpoints relevant for charged-particle radiotherapy. This supports a more physics-based m…
physics.med-ph2025
Scenario-free robust optimization algorithm for IMRT and IMPT treatment planning
Remo Cristoforetti, Jennifer Josephine Hardt, Niklas Wahl
Robust treatment planning algorithms for Intensity Modulated Proton Therapy (IMPT) and Intensity Modulated Radiation Therapy (IMRT) allow for uncertainty reduction in the delivered…