output
20022026
most citedMultilayer Networks

3.2k citations

Showing q-bio.PEShow all

16 papers · 1 filter

q-bio.PE2025★ 1 cited

Optimization of sequential therapies to maximize extinction of resistant bacteria through collateral sensitivity

Javier Molina-Hernández, José A. Cuesta, Beatriz Pascual-Escudero +2

Antimicrobial resistance (AMR) threatens global health. A promising and underexplored strategy to tackle this problem is sequential therapies exploiting collateral sensitivity (CS)…

q-bio.PE2024★ 1 cited

Eco-evolutionary constraints for the endemicity of rapidly evolving viruses

David Soriano-Paños

Antigenic escape constitutes the main mechanism allowing rapidly evolving viruses to achieve endemicity. Beyond granting immune escape, empirical evidence also suggests that mutati…

q-bio.PE2024★ 8 cited

Non-equilibrium microbial dynamics unveil a new macroecological pattern beyond Taylor's law

José Camacho-Mateu, Aniello Lampo, Saúl Ares +1

We introduce a comprehensive analytical benchmark, relying on Fokker-Planck formalism, to study microbial dynamics in presence of both biotic and abiotic forces. In equilibrium, we…

q-bio.PE2020★ 166 cited

Predictability: Can the turning point and end of an expanding epidemic be precisely forecast?

Mario Castro, Saúl Ares, José A. Cuesta +1

No, they can't. Epidemic spread is characterized by exponentially growing dynamics, which are intrinsically unpredictable. The time at which the growth in the number of infected in…

q-bio.PE2020★ 110 cited

From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics

Susanna Manrubia, José A. Cuesta, Jacobo Aguirre +15

Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the next major missing piece in a fully predictive theory of evolution. We refer to t…

q-bio.PE2018★ 52 cited

On the networked architecture of genotype spaces and its critical effects on molecular evolution

Jacobo Aguirre, Pablo Catalán, José A. Cuesta +1

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inhe…

q-bio.PE2017★ 36 cited

Distribution of phenotype sizes in sequence-to-structure genotype-phenotype maps

Susanna Manrubia, Jose A. Cuesta

An essential quantity to ensure evolvability of populations is the navigability of the genotype space. Navigability relies on the existence of sufficiently large genotype networks,…

q-bio.PE2016★ 16 cited

Sheldon Spectrum and the Plankton Paradox: Two Sides of the Same Coin. A trait-based plankton size-spectrum model

José A. Cuesta, Gustav W. Delius, Richard Law

The Sheldon spectrum describes a remarkable regularity in aquatic ecosystems: the biomass density as a function of logarithmic body mass is approximately constant over many orders…

q-bio.PE2016★ 14 cited

Enumerating secondary structures and structural moieties for circular RNAs

José A. Cuesta, Susanna Manrubia

A quantitative characterization of the relationship between molecular sequence and structure is essential to improve our understanding of how function emerges. This particular geno…

q-bio.PE2013★ 57 cited

Host mobility drives pathogen competition in spatially structured populations

Chiara Poletto, Sandro Meloni, Vittoria Colizza +2

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergenc…

q-bio.PE2013★ 32 cited

Evolution on neutral networks accelerates the ticking rate of the molecular clock

Susanna Manrubia, José A. Cuesta

Large sets of genotypes give rise to the same phenotype because phenotypic expression is highly redundant. Accordingly, a population can accept mutations without altering its pheno…

q-bio.PE2012★ 27 cited

On the coexistence of cooperators, defectors and conditional cooperators in the multiplayer iterated Prisoner's Dilemma

Jelena Grujić, José A. Cuesta, Angel Sánchez

Recent experimental evidence [Grujić et al., PLoS ONE 5, e13749 (2010)] on the spatial Prisoner's Dilemma suggests that players choosing to cooperate or not on the basis of their p…

q-bio.PE2009★ 785 cited

Evolutionary game theory: Temporal and spatial effects beyond replicator dynamics

Carlos P. Roca, José A. Cuesta, Angel Sánchez

Evolutionary game dynamics is one of the most fruitful frameworks for studying evolution in different disciplines, from Biology to Economics. Within this context, the approach of c…

q-bio.PE2009★ 67 cited

Promotion of cooperation on networks? The myopic best response case

Carlos P. Roca, Jose A. Cuesta, Angel Sanchez

We address the issue of the effects of considering a network of contacts on the emergence of cooperation on social dilemmas under myopic best response dynamics. We begin by summari…

q-bio.PE2007★ 27 cited

The Shared Reward Dilemma

J. A. Cuesta, R. Jimenez, H. Lugo +1

One of the most direct human mechanisms of promoting cooperation is rewarding it. We study the effect of sharing a reward among cooperators in the most stringent form of social dil…

q-bio.PE2005

The importance of selection rate in the evolution of cooperation

Carlos P. Roca, Jose A. Cuesta, Angel Sanchez

How cooperation emerges in human societies is still a puzzle. Evolutionary game theory has been the standard framework to address this issue. In most models, every individual plays…