output
20162025
most citedIn vivo optical imaging of physiological responses to photostimulation in human photoreceptors

239 citations

8 papers

physics.optics2025★ 3 cited

Measuring choriocapillaris blood flow with laser Doppler optical coherence tomography

Léo Puyo, Jonas Franke, Lisa Kutzner +3

We report on using a laser Doppler processing of Fourier-domain optical coherence tomography (OCT) data for the assessment of pulsatile blood flow in the choriocapillaris. Signal f…

physics.med-ph2021★ 9 cited

Retinal blood flow imaging with combined full-field swept-source optical coherence tomography and laser Doppler holography

Léo Puyo, Hendrik Spahr, Clara Pfäffle +2

Full-field swept-source optical coherence tomography (FF-SS-OCT) and laser Doppler holography (LDH) are two holographic imaging techniques presenting unique capabilities for ophtha…

physics.med-ph2020

Zero roll-off retinal MHz-OCT using an FDML-Laser

Julian Klee, Jan Philip Kolb, Christin Grill +3

Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these tec…

physics.med-ph2020★ 2 cited

Virtual H&E Histology by Fiber-Based Picosecond Two-Photon Microscopy

Jan Philip Kolb, Daniel Weng, Hubertus Hakert +10

Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, H&E equival…

physics.med-ph2020★ 7 cited

Dynamic contrast in scanning microscopic OCT

Michael Münter, Malte vom Endt, Mario Pieper +7

While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By ev…

physics.bio-ph2018★ 5 cited

Functional imaging of ganglion and receptor cells in living human retina by osmotic contrast

Clara Pfäffle, Dierck Hillmann, Hendrik Spahr +5

Imaging neuronal activity non-invasively in vivo is of tremendous interest, but current imaging techniques lack either functional contrast or necessary microscopic resolution. The…

physics.optics2017★ 36 cited

Off-axis reference beam for full-field swept-source OCT and holoscopy

Dierck Hillmann, Hendrik Spahr, Helge Sudkamp +4

In numerous applications, Fourier-domain optical coherence tomography (FD-OCT) suffers from a limited imaging depth due to signal roll-off, a limited focal range, and autocorrelati…

physics.med-ph2016★ 239 cited

In vivo optical imaging of physiological responses to photostimulation in human photoreceptors

Dierck Hillmann, Hendrik Spahr, Clara Pfäffle +3

Non-invasive functional imaging of molecular and cellular processes of vision is expected to have immense impact on research and clinical diagnostics. Although suitable intrinsic o…