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20172025
most citedStatistical learning of spatiotemporal patterns from longitudinal manifold-valued networks

10 citations

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stat.AP2024★ 1 cited

Straightforward Phase I Dose-Finding Design for Healthy Volunteers Accounting for Surrogate Activity Biomarkers

Sandrine Boulet, Emmanuelle Comets, Antoine Guillon +5

Conventionally, a first-in-human phase I trial in healthy volunteers aims to confirm the safety of a drug in humans. In such situations, volunteers should not suffer from any safet…