169 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- MRC Biostatistics UnitGB5 papers
- University of CambridgeGB5 papers
- Imperial College LondonGB3 papers
- The Alan Turing InstituteGB3 papers
- University of ManchesterGB3 papers
- Harvard UniversityUS2 papers
- Institut de Radioprotection et de Sûreté NucléaireFR2 papers
- Manchester University NHS Foundation TrustGB2 papers
- University College LondonGB2 papers
- University of LiverpoolGB2 papers
- University of OxfordGB2 papers
- Addenbrooke's HospitalGB1 paper
16 papers
Data needs for integrated economic-epidemiological models of pandemic mitigation policies
David J. Haw, Christian Morgenstern, Giovanni Forchini +4
The COVID-19 pandemic and the mitigation policies implemented in response to it have resulted in economic losses worldwide. Attempts to understand the relationship between economic…
A comparison of two frameworks for multi-state modelling, applied to outcomes after hospital admissions with COVID-19
Christopher Jackson, Brian Tom, Peter Kirwan +5
We compare two multi-state modelling frameworks that can be used to represent dates of events following hospital admission for people infected during an epidemic. The methods are a…
Novel methods for estimating the instantaneous and overall COVID-19 case fatality risk among care home residents in England
Christopher E. Overton, Luke Webb, Uma Datta +10
The COVID-19 pandemic has had high mortality rates in the elderly and frail worldwide, particularly in care homes. This is driven by the difficulty of isolating care homes from the…
Monte Carlo calculation of organ and effective dose rates from ground contaminated by Am 241: Results of an international intercomparison exercise
J Eakins, C Huet, H Brkić +12
An intercomparison exercise is described that examines Monte Carlo modelling of anthropomorphic voxel phantoms in an idealized ground-contamination photon exposure scenario. Thirte…
EURADOS Intercomparison on the Usage of the ICRP/ICRU Adult Reference Computational Phantoms
Maria Zankl, Jonathan Eakins, Jose-Maria Gomez Ros +6
The European Radiation Dosimetry Group, EURADOS, has organised an intercomparison study on the usage of the ICRP/ICRU voxel reference computational phantoms together with radiation…
Hospitalisation risk for COVID-19 patients infected with SARS-CoV-2 variant B.1.1.7: cohort analysis
Tommy Nyberg, Katherine A. Twohig, Ross J. Harris +7
Objective: To evaluate the relationship between coronavirus disease 2019 (COVID-19) diagnosis with SARS-CoV-2 variant B.1.1.7 (also known as Variant of Concern 202012/01) and the r…
A joint bayesian space-time model to integrate spatially misaligned air pollution data in R-INLA
Chiara Forlani, Samir Bhatt, Michela Cameletti +2
In air pollution studies, dispersion models provide estimates of concentration at grid level covering the entire spatial domain, and are then calibrated against measurements from m…
Shut and re-open: the role of schools in the spread of COVID-19 in Europe
Helena B. Stage, Joseph Shingleton, Sanmitra Ghosh +3
We investigate the effect of school closure and subsequent reopening on the transmission of COVID-19, by considering Denmark, Norway, Sweden, and German states as case studies. By…
Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example
Christopher E. Overton, Helena B. Stage, Shazaad Ahmad +16
During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and desig…
Tracking COVID-19 using online search
Vasileios Lampos, Maimuna S. Majumder, Elad Yom-Tov +6
Previous research has demonstrated that various properties of infectious diseases can be inferred from online search behaviour. In this work we use time series of online search que…
A mathematical study of CD8+ T cell responses calibrated with human data
John Paul Gosling, Sheeja M. Krishnan, Grant Lythe +3
Complete understanding of the mechanisms regulating the proliferation and differentiation that takes place during human immune CD8+ T cell responses is still lacking. Human clinica…
Label-free optical vibrational spectroscopy to detect the metabolic state of M. tuberculosis cells at the site of disease
Vincent O. Baron, Mingzhou Chen, Simon O. Clark +4
Tuberculosis relapse is a barrier to shorter treatment. It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a major role. Most studies investigat…
Exploiting routinely collected severe case data to monitor and predict influenza outbreaks
Alice Corbella, Xu-Sheng Zhang, Paul J. Birrell +4
Influenza remains a significant burden on health systems. Effective responses rely on the timely understanding of the magnitude and the evolution of an outbreak. For monitoring pur…
A pathway-based network analysis of hypertension-related genes
Huan Wang, Jing-Bo Hu, Chuan-Yun Xu +5
Complex network approach has become an effective way to describe interrelationships among large amounts of biological data, which is especially useful in finding core functions and…
Identifying lineage effects when controlling for population structure improves power in bacterial association studies
Sarah G Earle, Chieh-Hsi Wu, Jane Charlesworth +16
Bacteria pose unique challenges for genome-wide association studies (GWAS) because of strong structuring into distinct strains and substantial linkage disequilibrium across the gen…
Reconstructing transmission trees for communicable diseases using densely sampled genetic data
Colin J. Worby, Philip D. O'Neill, Theodore Kypraios +5
Whole genome sequencing of pathogens from multiple hosts in an epidemic offers the potential to investigate who infected whom with unparalleled resolution, potentially yielding imp…