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11 papers · 1 filter
Double diffusion encoding and applications for biomedical imaging
Rafael N. Henriques, Marco Palombo, Sune N. Jespersen +3
Diffusion Magnetic Resonance Imaging (dMRI) is one of the most important contemporary non-invasive modalities for probing tissue structure at the microscopic scale. The majority of…
Validation and noise robustness assessment of microscopic anisotropy estimation with clinically feasible double diffusion encoding MRI
Leevi Kerkelä, Rafael Neto Henriques, Matt G. Hall +2
Purpose: Double diffusion encoding (DDE) MRI enables the estimation of microscopic diffusion anisotropy, yielding valuable information on tissue microstructure. A recent study prop…
Short echo time relaxation-enhanced MR spectroscopy reveals broad downfield resonances
Sónia I. Gonçalves, Clémence Ligneul, Noam Shemesh
Purpose: Most MR spectroscopy (MRS) pulse sequences rely on broadband excitation with water saturation and typically focus on upfield signals. By contrast, the downfield spectrum,…
Evaluation of principal component analysis image denoising on multi-exponential MRI relaxometry
Mark D. Does, Jonas Lynge Olesen, Kevin D. Harkins +4
PURPOSE: Multi-exponential relaxometry is a powerful tool for characterizing tissue, but generally requires high image signal-to-noise ratio (SNR). This work evaluates the use of p…
Microscopic anisotropy misestimation in spherical-mean single diffusion encoding MRI
Rafael Neto Henriques, Sune N Jespersen, Noam Shemesh
Purpose: Microscopic fractional anisotropy (μFA) can disentangle microstructural information from orientation dispersion. While double diffusion encoding (DDE) MRI methods are wide…
Insights into brain microstructure from in vivo DW-MRS
Marco Palombo, Noam Shemesh, Itamar Ronen +1
Many developmental processes, such as plasticity and aging, or pathological processes such as neurological diseases are characterized by modulations of specific cellular types and…