108 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- Université de ToursFR15 papers
- Centre National de la Recherche ScientifiqueFR14 papers
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementFR7 papers
- Centre Inria de SaclayFR4 papers
- Institut national de recherche en sciences et technologies du numériqueFR4 papers
- Université Paris-SaclayFR4 papers
- École PolytechniqueFR3 papers
- Le StudiumFR3 papers
- University of Bío-BíoCL3 papers
- Biologie des oiseaux et avicultureFR2 papers
- Institut National de la Recherche AgronomiqueMA2 papers
- PharmaReview CorporationUS2 papers
19 papers
Mixed genetic background better recapitulates developmental and psychiatric phenotypes and heterogeneity than inbred C57BL/6J mice
Ana Dudas, Ana Novak, Caroline Gora +4
Preclinical models of neurodevelopmental and psychiatric conditions often rely on inbred mouse strains like C57BL/6J (B6), which exhibit limited genetic and behavioral variability.…
The insertion of Neomycin cassette impairs maternal and social behaviors in Arc/Arg3.1 knock-out mice
Ana Dudas, Emilia Caire, Abdurahman Hassan a Kuku +14
The Neomycin resistance cassette (Neo+) is commonly inserted in the genome of mice to generate knock-out (KO) models. The effect of gene deletion on social behaviors in mice is con…
Generalizing the SINDy approach with nested neural networks
Camilla Fiorini, Clément Flint, Louis Fostier +4
Symbolic Regression (SR) is a widely studied field of research that aims to infer symbolic expressions from data. A popular approach for SR is the Sparse Identification of Nonlinea…
Long-time asymptotic of the Lifshitz-Slyozov equation with nucleation
Juan Calvo, Erwan Hingant, Romain Yvinec
We consider the Lifshitz-Slyozov model with inflow boundary conditions of nucleation type. We show that for a collection of representative rate functions the size distributions app…
Interactions between -endorphin and kisspeptin neurons of the ewe arcuate nucleus are modulated by photoperiod
Vincent Hellier, Hugues Dardente, Didier Lomet +2
Opioid peptides are well-known modulators of the central control of reproduction. Among them, dynorphin coexpressed in kisspeptin (KP) neurons of the arcuate nucleus (ARC) has been…
Quasi-stationary distribution and metastability for the stochastic Becker-Döring model
Erwan Hingant, Romain Yvinec
We study a stochastic version of the classical Becker-Döring model, a well-known kinetic model for cluster formation that predicts the existence of a long-lived metastable state be…
The Initial-boundary value problem for the Lifshitz-Slyozov equation with non-smooth rates at the boundary
Juan Calvo, Erwan Hingant, Romain Yvinec
We prove existence and uniqueness of solutions to the initial-boundary value problem for the Lifshitz--Slyozov equation (a nonlinear transport equation on the half-line), focusing…
Profiling of FSHR Negative Allosteric Modulators on LH/CGR Reveals Biased Antagonism with Implications in Steroidogenesis
Mohammed Akli Ayoub, Romain Yvinec, Gwenhaël Jégot +5
Biased signaling has recently emerged as an interesting mean to modulate the function of many G protein-coupled receptors (GPCRs). Previous studies reported two negative allosteric…
Advances in computational modeling approaches in pituitary gonadotropin signaling
Romain Yvinec, Pascale Crépieux, Eric Reiter +2
Pituitary gonadotropins play an essential and pivotal role in the control of human and animal reproduction within the hypothalamic-pituitary-gonadal (HPG) axis. The computational m…
Follicle-stimulating hormone receptor: Advances and remaining challenges
Francesco De Pascali, Aurélie Tréfier, Flavie Landomiel +6
Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells of…
Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors
Laura Riccetti, Romain Yvinec, Danièle Klett +6
Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) have been considered biologically equivalent because of their structural similarities and their binding to the same…
Computational modeling approaches in gonadotropin signaling
Mohammed Akli Ayoub, Romain Yvinec, Pascale Crépieux +1
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) play essential roles in animal reproduction. They exert their function through binding to their cognate receptors, w…
The Becker-Döring process: pathwise convergence and phase transition phenomena
Erwan Hingant, Romain Yvinec
In this note, we study an infinite reaction network called the stochastic Becker-Döring process, a sub-class of the general coagulation-fragmentation models. We prove pathwise conv…
Probabilistic and Piecewise Deterministic models in Biology
Bertrand Cloez, Renaud Dessalles, Alexandre Genadot +3
We present recent results on Piecewise Deterministic Markov Processes (PDMPs), involved in biological modeling. PDMPs, first introduced in the probabilistic literature by Davis (19…
First passage times in homogeneous nucleation: dependence on the total number of particles
Romain Yvinec, Samuel Bernard, Erwan Hingant +1
Motivated by nucleation and molecular aggregation in physical, chemical and biological settings, we present an extension to a thorough analysis of the stochastic self-assembly of a…
A New Local Score Based Method Applied to Behavior-divergent Quail Lines Sequenced in Pools Precisely Detects Selection Signatures on Genes Related to Autism
Maria-Ines Fariello, Simon Boitard, Sabine Mercier +12
Detecting genomic footprints of selection is an important step in the understanding of evolution. Accounting for linkage disequilibrium in genome scans allows increasing the detect…
Boundary value for a nonlinear transport equation emerging from a stochastic coagulation-fragmentation type model
Julien Deschamps, Erwan Hingant, Romain Yvinec
We investigate the connection between two classical models of phase transition phenomena, the (discrete size) stochastic Becker-Döring, a continous time Markov chain model, and the…
DynPeak : An algorithm for pulse detection and frequency analysis in hormonal time series
Alexandre Vidal, Qinghua Zhang, Claire Médigue +2
The endocrine control of the reproductive function is often studied from the analysis of luteinizing hormone (LH) pulsatile secretion by the pituitary gland. Whereas measurements i…
Endogenous circannual rhythm in LH secretion: insight from signal analysis coupled with mathematical modelling
Alexandre Vidal, Claire Médigue, Benoit Malpaux +1
In sheep as in many vertebrates, the seasonal pattern of reproduction is timed by the annual photoperiodic cycle, characterized by seasonal changes in the daylength. The photoperio…