108 citations · 155 across the 4 of their papers we have counts for
4 papers
Profiling of FSHR Negative Allosteric Modulators on LH/CGR Reveals Biased Antagonism with Implications in Steroidogenesis
Mohammed Akli Ayoub, Romain Yvinec, Gwenhaël Jégot +5
Biased signaling has recently emerged as an interesting mean to modulate the function of many G protein-coupled receptors (GPCRs). Previous studies reported two negative allosteric…
Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors
Laura Riccetti, Romain Yvinec, Danièle Klett +6
Human luteinizing hormone (LH) and chorionic gonadotropin (hCG) have been considered biologically equivalent because of their structural similarities and their binding to the same…
Computational modeling approaches in gonadotropin signaling
Mohammed Akli Ayoub, Romain Yvinec, Pascale Crépieux +1
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) play essential roles in animal reproduction. They exert their function through binding to their cognate receptors, w…
Workflow description to dynamically model β-arrestin signaling networks
Romain Yvinec, Mohammed Akli Ayoub, Francesco De Pascali +3
Dynamic models of signaling networks allow the formulation of hypotheses on the topology and kinetic rate laws characterizing a given molecular network, in-depth exploration and co…