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20082024
most citedFederated Learning Enables Big Data for Rare Cancer Boundary Detection

390 citations

Showing q-bio.TOShow all

6 papers · 1 filter

q-bio.TO2015★ 24 cited

Modulation of transforming growth factor beta signalling pathway genes by transforming growth factor beta in human osteoarthritic chondrocytes: involvement of Sp1 in both early and late response cells to transforming growth factor beta

Catherine Baugé, Olivier Cauvard, Sylvain Leclercq +2

Transforming growth factor beta (TGF) plays a central role in morphogenesis, growth, and cell differentiation. This cytokine is particularly important in cartilage where it regu…

q-bio.TO2014★ 1 cited

Bridging scales in cancer progression: Mapping genotype to phenotype using neural networks

Philip Gerlee, Eunjung Kim, Alexander R. A. Anderson

In this review we summarize our recent efforts in trying to understand the role of heterogeneity in cancer progression by using neural networks to characterise different aspects of…

q-bio.TO2013

Mathematical modeling of the metastatic process

Jacob G. Scott, Philip Gerlee, David Basanta +3

Mathematical modeling in cancer has been growing in popularity and impact since its inception in 1932. The first theoretical mathematical modeling in cancer research was focused on…

q-bio.TO2013★ 1 cited

Exploiting ecological principles to better understand cancer progression and treatment

David Basanta, Alexander R. A. Anderson

A small but growing number of people are finding interesting parallels between ecosystems as studied by ecologists (think of a Savanna or the Amazon rain forest or a Coral reef) an…

q-bio.TO2012★ 61 cited

A mathematical model of tumor self-seeding reveals secondary metastatic deposits as drivers of primary tumor growth

Jacob G Scott, David Basanta, Alexander R. A. Anderson +1

Two models of circulating tumor cell (CTC) dynamics have been proposed to explain the phenomenon of tumor 'self-seeding', whereby CTCs repopulate the primary tumor and accelerate g…

q-bio.TO2008

A Spatial Model of Tumor-Host Interaction: Application of Chemotherapy

Peter Hinow, Philip Gerlee, Lisa J. McCawley +9

In this paper we consider chemotherapy in a spatial model of tumor growth. The model, which is of reaction-diffusion type, takes into account the complex interactions between the t…