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- Universitätsmedizin GöttingenDE33 papers
- University of GöttingenDE26 papers
- Graz University of TechnologyAT12 papers
- BioTechMed-GrazAT7 papers
- Nanoscale Microscopy and Molecular Physiology of the Brain Cluster of Excellence 171 — DFG Research Center 103DE7 papers
- Heidelberg UniversityDE6 papers
- University Hospital HeidelbergDE6 papers
- Charité - Universitätsmedizin BerlinDE5 papers
- Max Planck Institute for Dynamics and Self-OrganizationDE5 papers
- Ludwig-Maximilians-Universität MünchenDE4 papers
- Max Planck Institute for Biophysical ChemistryDE4 papers
- Advanced Imaging Research (United States)US3 papers
4 papers · 1 filter
Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project
M. Zabel, S. Schlögl, A. Lubinski +45
BACKGROUND. The clinical effectiveness of primary prevention implantable cardioverter defibrillator (ICD) therapy is under debate. It is urgently needed to better identify patients…
Group sequential designs for negative binomial outcomes
Tobias Mütze, Ekkehard Glimm, Heinz Schmidli +1
Count data and recurrent events in clinical trials, such as the number of lesions in magnetic resonance imaging in multiple sclerosis, the number of relapses in multiple sclerosis,…
Sample size re-estimation incorporating prior information on a nuisance parameter
Tobias Mütze, Heinz Schmidli, Tim Friede
Prior information is often incorporated informally when planning a clinical trial. Here, we present an approach on how to incorporate prior information, such as data from historica…
Blinded sample size re-estimation in three-arm trials with 'gold standard' design
Tobias Mütze, Tim Friede
The sample size of a clinical trial relies on information about nuisance parameters such as the outcome variance. When no or only limited information is available, it has been prop…