output
20122025
most citedKMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation

119 citations

10 papers

q-bio.NC2025★ 119 cited

KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation

L Cif, D Demailly, JP Lin +112

Heterozygous mutations in KMT2B are associated with an early-onset, progressive, and often complex dystonia (DYT28). Key characteristics of typical disease include focal motor feat…

physics.comp-ph2021★ 42 cited

Human learning for molecular simulations: the Collective Variables Dashboard in VMD

Jérôme Hénin, Laura J. S. Lopes, Giacomo Fiorin

The Collective Variables Dashboard is a software tool for real-time, seamless exploration of molecular structures and trajectories in a customizable space of collective variables.…

physics.app-ph2019★ 4 cited

Rapid, Quantitative Therapeutic Screening for Alzheimer's Enzymes Enabled by Optimal Signal Transduction with Transistors

Son T. Le, Michelle A. Morris, Antonio Cardone +6

We show that simple, commercially sourced n-channel silicon field-effect transistors (nFETs) operating under closed loop control exhibit an ~3-fold improvement in pH readout resolu…

q-bio.QM2019★ 16 cited

Quantum Capacitance-Limited MoS2 Biosensors Enable Remote Label-Free Enzyme Measurements

Son T. Le, Nicholas B. Guros, Robert C. Bruce +7

We have demonstrated atomically thin, quantum capacitance-limited, field-effect transistors (FETs) that enable the detection of pH changes with ~75-fold higher sensitivity (4.4 V/p…

stat.AP2015★ 1 cited

Relating multi-sequence longitudinal intensity profiles and clinical covariates in new multiple sclerosis lesions

Elizabeth M. Sweeney, Russell T. Shinohara, Blake E. Dewey +5

Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process inv…

astro-ph.SR2015★ 59 cited

Survival and Structure of Dusty Vortices in Protoplanetary Discs

Ivo Crnkovic-Rubsamen, Zhaohuan Zhu, James M. Stone

We have studied the impact of dust feedback on the survival and structure of vortices in protoplanetary discs using 2-D shearing box simulations with Lagrangian dust particles. We…

stat.AP2015★ 46 cited

Longitudinal high-dimensional principal components analysis with application to diffusion tensor imaging of multiple sclerosis

Vadim Zipunnikov, Sonja Greven, Haochang Shou +3

We develop a flexible framework for modeling high-dimensional imaging data observed longitudinally. The approach decomposes the observed variability of repeatedly measured high-dim…

q-bio.NC2014

Spatiotemporal Dissociation of Brain Activity underlying Subjective Awareness, Objective Performance and Confidence

Qi Li, Zachary Hill, Biyu J. He

Despite intense recent research, the neural correlates of conscious visual perception remain elusive. The most established paradigm for studying brain mechanisms underlying conscio…

stat.AP2013

Soft Null Hypotheses: A Case Study of Image Enhancement Detection in Brain Lesions

Haochang Shou, Russell T. Shinohara, Han Liu +2

This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain…

cond-mat.supr-con2012

Reply to "Comment on `Fluctuation-induced first-order transition in p-wave superconductors'"

Qi Li, D. Belitz, John Toner

This is a Reply to the Comment posted as arXiv:1207.1261.