activity
20132026
most citedLongitudinal high-dimensional principal components analysis with application to diffusion tensor imaging of multiple sclerosis

46 citations · 72 across the 16 of their papers we have counts for

collaborators

16 papers

cs.CV2026

GenFAR: A generalized representation of brain structure, derived from 49,246 multi-cohort MRIs via deep learning

Vishnu M. Bashyam, Guray Erus, Junhao Wen +29

Deep learning models for neuroimaging have largely been developed for individual tasks, limiting knowledge transfer across applications. Here we introduce GenFAR, a modular deep le…

q-bio.QM2024

Generative models of MRI-derived neuroimaging features and associated dataset of 18,000 samples

Sai Spandana Chintapalli, Rongguang Wang, Zhijian Yang +7

Availability of large and diverse medical datasets is often challenged by privacy and data sharing restrictions. For successful application of machine learning techniques for disea…

q-bio.QM2023★ 3 cited

Gene-SGAN: a method for discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering

Zhijian Yang, Junhao Wen, Ahmed Abdulkadir +25

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multipl…

stat.AP2022

Mediation analysis with densities as mediators with an application to iCOMPARE trial

Jingru Zhang, Mathias Basner, Christopher W. Jones +3

Physical activity has long been shown to be associated with biological and physiological performance and risk of diseases. It is of great interest to assess whether the effect of a…

stat.ME2022

Empirical Likelihood Inference of Variance Components in Linear Mixed-Effects Models

J. Zhang, W. Guo, J. S. Carpenter +6

Linear mixed-effects models are widely used in analyzing repeated measures data, including clustered and longitudinal data, where inferences of both fixed effects and variance comp…

q-bio.NC2021

Multidimensional representations in late-life depression: convergence in neuroimaging, cognition, clinical symptomatology and genetics

Junhao Wen, Cynthia H. Y. Fu, Duygu Tosun +22

Late-life depression (LLD) is characterized by considerable heterogeneity in clinical manifestation. Unraveling such heterogeneity would aid in elucidating etiological mechanisms a…