output
20132026
most citedAncient human genomes suggest three ancestral populations for present-day Europeans

1.5k citations

16 papers

cs.CV2026

Deep Learning Pose Estimation for Multi-Label Recognition of Combined Hyperkinetic Movement Disorders

Laura Cif, Diane Demailly, Gabriella A. Horvàth +15

Hyperkinetic movement disorders (HMDs) such as dystonia, tremor, chorea, myoclonus, and tics are disabling motor manifestations across childhood and adulthood. Their fluctuating, i…

eess.SP2026

Absorption mode broadband 2D MS for proteomics and metabolomics

Maria A van Agthoven, Marek Polák, Jan Fiala +9

Two-dimensional mass spectrometry (2D MS) is a method for tandem mass spectrometry that enables the correlation between precursor and fragment ions without the need for ion isolati…

q-bio.QM2025

Impact of Force Field Polarization on Correlated Motions of Proteins

Ana Milinski, Annick Dejaegere, Roland Stote

Correlated motions of proteins underpin many physiological mechanisms, such as substrate binding, signal transduction, enzymatic activity and allostery. These motions arise from lo…

q-bio.GN2020★ 71 cited

TMEM240 mutations cause spinocerebellar ataxia 21 with mental retardation and severe cognitive impairment

Jérôme Delplanque, David Devos, Vincent Huin +18

Autosomal dominant cerebellar ataxia corresponds to a clinically and genetically heterogeneous group of neurodegenerative disorders that primarily affect the cerebellum. Here, we r…

q-bio.QM2019★ 4 cited

How to orient cells in micro-cavities for high resolution imaging of cytokinesis and lumen formation

Alka Bhat, Linjie Lu, Chen-Ho Wang +4

Imaging dynamics of cellular morphogenesis with high spatial-temporal resolution in 3D is challenging, due to the low spatial resolution along the optical axis and photo-toxicity.…

q-bio.BM2019★ 10 cited

BpForms and BcForms: Tools for concretely describing non-canonical polymers and complexes to facilitate comprehensive biochemical networks

Paul F. Lang, Yassmine Chebaro, Xiaoyue Zheng +4

Although non-canonical residues, caps, crosslinks, and nicks play an important role in the function of many DNA, RNA, proteins, and complexes, we do not fully understand how networ…

cs.DL2017★ 128 cited

Sustainable computational science: the ReScience initiative

Nicolas P. Rougier, Konrad Hinsen, Frédéric Alexandre +42

Computer science offers a large set of tools for prototyping, writing, running, testing, validating, sharing and reproducing results, however computational science lags behind. In…

physics.data-an2016★ 34 cited

PALMA, an improved algorithm for DOSY signal processing

Afef Cherni, Emilie Chouzenoux, Marc-André Delsuc

NMR is a tool of choice for the measure of diffusion coefficients of species in solution. The DOSY experiment, a 2D implementation of this measure, has proven to be particularly us…

physics.bio-ph2015★ 21 cited

Spatial fluctuations at vertices of epithelial layers: quantification of regulation by Rho pathway

É. Fodor, V. Mehandia, J. Comelles +5

In living matter, shape fluctuations induced by acto-myosin are usually studied in vitro via reconstituted gels, whose properties are controlled by changing the concentrations of a…

stat.AP2015★ 10 cited

The Gibbs-plaid biclustering model

Thierry Chekouo, Alejandro Murua, Wolfgang Raffelsberger

We propose and develop a Bayesian plaid model for biclustering that accounts for the prior dependency between genes (and/or conditions) through a stochastic relational graph. This…

q-bio.BM2015★ 10 cited

Duplex formation and secondary structure of γ-PNA observed by NMR and CD

J. M. P. Viéville, S. Barluenga, N. Winssinger +1

Peptide Nucleic Acids (PNA) are non-natural oligonucleotides mimics. γ-PNA backbone are formed by standard nucleic acids nucleobases connected by a neutral N-(2-aminoethyl)glycine…

physics.chem-ph2015★ 33 cited

Accurate DOSY measure of out-of-equilibrium systems by permutated DOSY (p-DOSY)

Maria Oikonomou, Julia Asencio Hernández, Aldrik H. Velders +1

NMR spectroscopy is an excellent tool for monitoring in-situ chemical reactions. In particular, DOSY measurement is well suited to characterize transient species by the determinati…

nucl-th2014★ 36 cited

Relation of E1 pygmy and toroidal resonances

V. O. Nesterenko, A. Repko, P. -G. Reinhard +1

A possible relation of the low-lying E1 (pygmy resonance) and toroidal strengths is analyzed by using Skyrme-RPA results for the strength functions, transition densities and curren…

astro-ph.IM2014

Building an Archive with Saada

Laurent Michel, Christian Motch, Hoan Ngoc Nguyen +1

Saada transforms a set of heterogeneous FITS files or VOTables of various categories (images, tables, spectra ...) in a database without writing code. Databases created with Saada…

q-bio.PE2013★ 1.5k cited

Ancient human genomes suggest three ancestral populations for present-day Europeans

Iosif Lazaridis, Nick Patterson, Alissa Mittnik +117

We sequenced genomes from a 7,000 year old early farmer from Stuttgart in Germany, an 8,000 year old hunter-gatherer from Luxembourg, and seven 8,000 year old hun…

q-bio.CB2013★ 87 cited

Protrusion fluctuations direct cell motion

David Caballero, Raphael Voituriez, Daniel Riveline

Many physiological phenomena involve directional cell migration. It is usually attributed to chemical gradients in vivo. Recently, other cues have been shown to guide cells in vitr…