6k citations
- University of Hawaiʻi at MānoaUS2 papers
- Agricultural Research ServiceUS1 paper
- Argonne National LaboratoryUS1 paper
- Barcelona Supercomputing CenterES1 paper
- Berkeley CollegeUS1 paper
- Brookhaven National LaboratoryUS1 paper
- Centre for Development of Advanced ComputingIN1 paper
- Centre Inria de l'Université de RennesFR1 paper
- Dana-Farber Cancer InstituteUS1 paper
- Dana-Farber/Harvard Cancer CenterUS1 paper
- DePaul UniversityUS1 paper
- FernUniversität in HagenDE1 paper
5 papers
Workflows Community Summit 2024: Future Trends and Challenges in Scientific Workflows
Rafael Ferreira da Silva, Deborah Bard, Kyle Chard +108
The Workflows Community Summit gathered 111 participants from 18 countries to discuss emerging trends and challenges in scientific workflows, focusing on six key areas: time-sensit…
Haplotype-resolved de novo assembly with phased assembly graphs
Haoyu Cheng, Gregory T Concepcion, Xiaowen Feng +2
Haplotype-resolved de novo assembly is the ultimate solution to the study of sequence variations in a genome. However, existing algorithms either collapse heterozygous alleles into…
RPM-Drive: A robust, safe, and reversible gene drive system that remains functional after 200+ generations
Floyd A. Reed, Todd G. Aquino-Michaels, Maria S. Costantini +2
Despite the advent of several novel, synthetic gene drive mechanisms and their potential to one-day control a number of devastating diseases, among other applications, practical us…
Near-optimal Assembly for Shotgun Sequencing with Noisy Reads
Ka-Kit Lam, Asif Khalak, David Tse
Recent work identified the fundamental limits on the information requirements in terms of read length and coverage depth required for successful de novo genome reconstruction from…
Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution
Daniël P. Melters, Keith R. Bradnam, Hugh A. Young +14
Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale…