output
20132025
most citedSignalling Entropy: a novel network-theoretical framework for systems analysis and interpretation of functional omic data

88 citations

6 papers

stat.ME2025★ 5 cited

Interpretable Transformation and Analysis of Timelines through Learning via Surprisability

Osnat Mokryn, Teddy Lazebnik, Hagit Ben Shoshan

The analysis of high-dimensional timeline data and the identification of outliers and anomalies is critical across diverse domains, including sensor readings, biological and medica…

q-bio.BM2024★ 3 cited

DiffPaSS -- High-performance differentiable pairing of protein sequences using soft scores

Umberto Lupo, Damiano Sgarbossa, Martina Milighetti +1

Identifying interacting partners from two sets of protein sequences has important applications in computational biology. Interacting partners share similarities across species due…

q-bio.GN2023★ 7 cited

Cancer-inspired Genomics Mapper Model for the Generation of Synthetic DNA Sequences with Desired Genomics Signatures

Teddy Lazebnik, Liron Simon-Keren

Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased…

q-bio.MN2015★ 54 cited

Increased signaling entropy in cancer requires the scale-free property of protein interaction networks

Andrew E. Teschendorff, Christopher R. S. Banerji, Simone Severini +2

One of the key characteristics of cancer cells is an increased phenotypic plasticity, driven by underlying genetic and epigenetic perturbations. However, at a systems-level it is u…

q-bio.MN2014★ 88 cited

Signalling Entropy: a novel network-theoretical framework for systems analysis and interpretation of functional omic data

Andrew Teschendorff, Peter Sollich, Reimer Kuehn

A key challenge in systems biology is the elucidation of the underlying principles, or fundamental laws, which determine the cellular phenotype. Understanding how these fundamental…

q-bio.MN2013★ 26 cited

Stress induces remodelling of yeast interaction and co-expression networks

Sonja Lehtinen, Francesc Xavier Marsellach, Sandra Codlin +6

Network analysis provides a powerful framework for the interpretation of genome-wide data. While static network approaches have proved fruitful, there is increasing interest in the…