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- National Cancer InstituteUS19 papers
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4 papers · 1 filter
Pathways of Distinction Analysis: a new technique for multi-SNP analysis of GWAS data
Rosemary Braun, Kenneth Buetow
Genome-wide association studies have become increasingly common due to advances in technology and have permitted the identification of differences in single nucleotide polymorphism…
The Augmented Lagrange Multiplier Method for Exact Recovery of Corrupted Low-Rank Matrices
Zhouchen Lin, Minming Chen, Yi Ma
This paper proposes scalable and fast algorithms for solving the Robust PCA problem, namely recovering a low-rank matrix with an unknown fraction of its entries being arbitrarily c…
Induced fit, conformational selection and independent dynamic segments: an extended view of binding events
Peter Csermely, Robin Palotai, Ruth Nussinov
Single molecule and NMR measurements of protein dynamics increasingly uncover the complexity of binding scenarios. Here we describe an extended conformational selection model which…
Coarse Graining RNA Nanostructures for Molecular Dynamics Simulations
Maxim Paliy, Roderick Melnik, Bruce A. Shapiro
A series of coarse-grained models have been developed for the study of the molecular dynamics of RNA nanostructures. The models in the series have one to three beads per nucleotide…