151 citations · 214 across the 2 of their papers we have counts for
2 papers
q-bio.MN2013★ 63 cited
Pathway drug cocktail: targeting Ras signaling based on structural pathways
Ruth Nussinov, Chung-Jung Tsai, Carla Mattos
Tumors bearing Ras mutations are notoriously difficult to treat. Drug combinations targeting the Ras protein or its pathway have also not met with success. Pathway drug cocktails,…
q-bio.MN2011★ 151 cited
Allo-network drugs: harnessing allostery in cellular networks
Ruth Nussinov, Chung-Jung Tsai, Peter Csermely
Allosteric drugs are increasingly used because they produce fewer side effects. Allosteric signal propagation does not stop at the 'end' of a protein, but may be dynamically transm…