output
20102026
most citedDirect-coupling analysis of residue co-evolution captures native contacts across many protein families

1.6k citations

researchers with a paper here

Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.

collaborating institutions
Showing 2017 · q-bio.MNShow all

6 papers · 2 filters

q-bio.MN2017★ 6 cited

Statistics of optimal information flow in ensembles of regulatory motifs

Andrea Crisanti, Andrea De Martino, Jonathan Fiorentino

Genetic regulatory circuits universally cope with different sources of noise that limit their ability to coordinate input and output signals. In many cases, optimal regulatory perf…

q-bio.MN2017★ 2 cited

Constraint-based inverse modeling of metabolic networks: a proof of concept

Daniele De Martino, Andrea De Martino

We consider the problem of inferring the probability distribution of flux configurations in metabolic network models from empirical flux data. For the simple case in which experime…

q-bio.MN2017★ 28 cited

ceRNA crosstalk stabilizes protein expression and affects the correlation pattern of interacting proteins

Araks Martirosyan, Andrea De Martino, Andrea Pagnani +1

Gene expression is a noisy process and several mechanisms, both transcriptional and posttranscriptional, can stabilize protein levels in cells. Much work has focused on the role of…

q-bio.MN2017★ 22 cited

Quantifying the entropic cost of cellular growth control

Daniele De Martino, Fabrizio Capuani, Andrea De Martino

We quantify the amount of regulation required to control growth in living cells by a Maximum Entropy approach to the space of underlying metabolic states described by genome-scale…

q-bio.MN2017★ 7 cited

Translating ceRNA susceptibilities into correlation functions

Araks Martirosyan, Matteo Marsili, Andrea De Martino

Competition to bind microRNAs induces an effective positive crosstalk between their targets, therefore known as `competing endogenous RNAs' or ceRNAs. While such an effect is known…

q-bio.MN2017★ 8 cited

Microenvironmental cooperation promotes early spread and bistability of a Warburg-like phenotype

Jorge Fernandez-de-Cossio-Diaz, Andrea De Martino, Roberto Mulet

We introduce an in silico model for the initial spread of an aberrant phenotype with Warburg-like overflow metabolism within a healthy homeostatic tissue in contact with a nutrient…