activity
20162022
most citedSimulating Organogenesis in COMSOL: Phase-Field Based Simulations of Embryonic Lung Branching Morphogenesis

8 citations · 22 across the 6 of their papers we have counts for

collaborators

6 papers

q-bio.QM2022

A New Hyperelastic Lookup Table for RT-DC

Lucas Daniel Wittwer, Felix Reichel, Paul Müller +2

Real-time deformability cytometry (RT-DC) is an established method that quantifies features like size, shape, and stiffness for whole cell populations on a single-cell level in rea…

physics.bio-ph2022★ 7 cited

On the role of mechanosensitive binding dynamics in the pattern formation of active surfaces

M. Bonati, L. D. Wittwer, S. Aland +1

The actin cortex of an animal cell is a thin polymeric layer attached to the inner side of the plasma membrane. It plays a key role in shape regulation and pattern formation on the…

cond-mat.soft2022★ 5 cited

A computational model of self-organized shape dynamics of active surfaces in fluids

Lucas D. Wittwer, Sebastian Aland

Mechanochemical processes on surfaces such as the cellular cortex or epithelial sheets, play a key role in determining patterns and shape changes of biological systems. To understa…

q-bio.TO2018

Simulation of morphogen and tissue dynamics

M. D. Peters, L. D. Wittwer, A. Stopka +3

Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modelling this process can provide novel insights into deve…

q-bio.QM2017★ 2 cited

Simulating Organogenesis in COMSOL: Comparison Of Methods For Simulating Branching Morphogenesis

Lucas D. Wittwer, Michael Peters, Sebastian Aland +1

During organogenesis tissue grows and deforms. The growth processes are controlled by diffusible proteins, so-called morphogens. Many different patterning mechanisms have been prop…

q-bio.QM2016★ 8 cited

Simulating Organogenesis in COMSOL: Phase-Field Based Simulations of Embryonic Lung Branching Morphogenesis

Lucas Daniel Wittwer, Roberto Croce, Sebastian Aland +1

Organogenesis has been studied for decades, but fundamental questions regarding the control of growth and shape remain unsolved. We have recently shown that of all proposed mathema…