96 citations · 135 across the 5 of their papers we have counts for
5 papers
The Origins of Transient Bimodality
Kaan Öcal, Augustinas Sukys, Aanjaneya Kumar +1
Many dynamical systems exhibit diverse modes of behavior. In biology, such modes can represent individual or cell fates. While the emergence of multimodality is commonly studied, t…
Cell size distributions in lineages
Kaan Öcal, Michael P. H. Stumpf
Cells actively regulate their size during the cell cycle to maintain volume homeostasis across generations. While various mathematical models of cell size regulation have been prop…
Model Reduction for the Chemical Master Equation: an Information-Theoretic Approach
K. Öcal, G. Sanguinetti, R. Grima
The complexity of mathematical models in biology has rendered model reduction an essential tool in the quantitative biologist's toolkit. For stochastic reaction networks described…
Parameter estimation for biochemical reaction networks using Wasserstein distances
Kaan Öcal, Ramon Grima, Guido Sanguinetti
We present a method for estimating parameters in stochastic models of biochemical reaction networks by fitting steady-state distributions using Wasserstein distances. We simulate a…
Flexible statistical inference for mechanistic models of neural dynamics
Jan-Matthis Lueckmann, Pedro J. Goncalves, Giacomo Bassetto +3
Mechanistic models of single-neuron dynamics have been extensively studied in computational neuroscience. However, identifying which models can quantitatively reproduce empirically…