16 citations · 25 across the 7 of their papers we have counts for
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q-bio.PE2018
Predicting influenza H3N2 vaccine efficacy from evolution of the dominant epitope
Melia E. Bonomo, Michael W. Deem
We predict vaccine efficacy with a measure of antigenic distance between influenza A(H3N2) and candidate vaccine viruses based on amino acid substitutions in the dominant epitopes.…
q-bio.PE2017★ 16 cited
The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas
Melia E. Bonomo, Michael W. Deem
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) constitute a multi-functional, constantly evolving immune system in bacteria…
q-bio.PE2017
How the other half lives: CRISPR-Cas's influence on bacteriophages
Melia E. Bonomo, Michael W. Deem
CRISPR-Cas is a genetic adaptive immune system unique to prokaryotic cells used to combat phage and plasmid threats. The host cell adapts by incorporating DNA sequences from invadi…