16 citations · 25 across the 7 of their papers we have counts for
7 papers
A small PAM optimises target recognition in the CRISPR-Cas immune system
Melia E. Bonomo
CRISPR-Cas is an adaptive immune mechanism that has been harnessed for a variety of genetic engineering applications: the Cas9 protein recognises a 2-5nt DNA motif, known as the PA…
Isabelle Stone: breaking the glass ceiling with thin films and teaching
Melia E. Bonomo
Physicist Isabelle Stone forged ahead in what was largely a men's profession in the early 1900s. She is credited as the first woman in the United States to obtain a Ph.D. in physic…
Music to My Ears: Neural modularity and flexibility differ in response to real-world music stimuli
Melia E. Bonomo, Anthony K. Brandt, J. Todd Frazier +1
Music listening involves many simultaneous neural operations, including auditory processing, working memory, temporal sequencing, pitch tracking, anticipation, reward, and emotion,…
Modularity allows classification of human brain networks during music and speech perception
Melia E. Bonomo, Christof Karmonik, Anthony K. Brandt +1
We investigate the use of modularity as a quantifier of whole-brain functional networks. Brain networks are constructed from functional magnetic resonance imaging while subjects li…
Predicting influenza H3N2 vaccine efficacy from evolution of the dominant epitope
Melia E. Bonomo, Michael W. Deem
We predict vaccine efficacy with a measure of antigenic distance between influenza A(H3N2) and candidate vaccine viruses based on amino acid substitutions in the dominant epitopes.…
The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas
Melia E. Bonomo, Michael W. Deem
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) constitute a multi-functional, constantly evolving immune system in bacteria…
How the other half lives: CRISPR-Cas's influence on bacteriophages
Melia E. Bonomo, Michael W. Deem
CRISPR-Cas is a genetic adaptive immune system unique to prokaryotic cells used to combat phage and plasmid threats. The host cell adapts by incorporating DNA sequences from invadi…