13 citations · 29 across the 18 of their papers we have counts for
Showing 2019Show all
3 papers · 1 filter
stat.ME2019★ 3 cited
Optimal curtailed designs for single arm phase II clinical trials
Martin Law, Michael J. Grayling, Adrian P. Mander
In single-arm phase II oncology trials, the most popular choice of design is Simon's two-stage design, which allows early stopping at one interim analysis. However, the expected tr…
stat.CO2019
A web application for the design of multi-arm clinical trials
Michael J Grayling, James MS Wason
Multi-arm designs provide an effective means of evaluating several treatments within the same clinical trial. Given the large number of treatments now available for testing in many…
stat.CO2019
A review of available software for adaptive clinical trial design
Michael J Grayling, Graham M Wheeler
Background/Aims: The increasing expense of the drug development process has seen interest in the use of adaptive designs (ADs) grow substantially in recent years. Accordingly, much…