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Large-scale analysis of disease pathways in the human interactome
Monica Agrawal, Marinka Zitnik, Jure Leskovec
Discovering disease pathways, which can be defined as sets of proteins associated with a given disease, is an important problem that has the potential to provide clinically actiona…
Learning Structural Node Embeddings Via Diffusion Wavelets
Claire Donnat, Marinka Zitnik, David Hallac +1
Nodes residing in different parts of a graph can have similar structural roles within their local network topology. The identification of such roles provides key insight into the o…
Jumping across biomedical contexts using compressive data fusion
Marinka Zitnik, Blaz Zupan
Motivation: The rapid growth of diverse biological data allows us to consider interactions between a variety of objects, such as genes, chemicals, molecular signatures, diseases, p…
Predicting multicellular function through multi-layer tissue networks
Marinka Zitnik, Jure Leskovec
Motivation: Understanding functions of proteins in specific human tissues is essential for insights into disease diagnostics and therapeutics, yet prediction of tissue-specific cel…