activity
20112023
most citedA multi-phenotypic cancer model with cell plasticity

48 citations · 190 across the 10 of their papers we have counts for

collaborators

10 papers

stat.AP2023

Bayesian Inference of Phenotypic Plasticity of Cancer Cells Based on Dynamic Model for Temporal Cell Proportion Data

Shuli Chen, Yuman Wang, Da Zhou +1

Mounting evidence underscores the prevalent hierarchical organization of cancer tissues. At the foundation of this hierarchy reside cancer stem cells, a subset of cells endowed wit…

q-bio.PE2020

Stochastic stem cell models with mutation: A comparison of asymmetric and symmetric divisions

Zhijie Wu, Yuman Wang, Kun Wang +1

In order to fulfill cell proliferation and differentiation through cellular hierarchy, stem cells can undergo either asymmetric or symmetric divisions. Recent studies pay special a…

q-bio.PE2019★ 20 cited

Evolution of cooperation driven by active information spreading

Bin Wu, Hye Jin Park, Lingshan Wu +1

Cooperators forgo their interest to benefit others. Thus cooperation should not be favored by natural selection. It challenges the evolutionists, since cooperation is widespread. A…

q-bio.CB2017★ 1 cited

A Bayesian statistical analysis of stochastic phenotypic plasticity model of cancer cells

Da Zhou, Shanjun Mao, Kaiyi Chen +2

The phenotypic plasticity of cancer cells has received special attention in recent years. Even though related models have been widely studied in terms of mathematical properties, a…

q-bio.PE2016★ 13 cited

Control of epidemics via social partnership adjustment

Bin Wu, Shanjun Mao, Jiazeng Wang +1

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shorten…

q-bio.CB2015★ 31 cited

The overshoot and phenotypic equilibrium in characterizing cancer dynamics of reversible phenotypic plasticity

Xiufang Chen, Yue Wang, Tianquan Feng +3

The paradigm of phenotypic plasticity indicates reversible relations of different cancer cell phenotypes, which extends the cellular hierarchy proposed by the classical cancer stem…

q-bio.CB2015★ 26 cited

The phenotypic equilibrium of cancer cells: From average-level stability to path-wise convergence

Yuanling Niu, Yue Wang, Da Zhou

The phenotypic equilibrium, i.e. heterogeneous population of cancer cells tending to a fixed equilibrium of phenotypic proportions, has received much attention in cancer biology ve…

q-bio.PE2014★ 17 cited

Phenotypic Equilibrium as Probabilistic Convergence in Multi-phenotype Cell Population Dynamics

Da-Quan Jiang, Yue Wang, Da Zhou

We consider the cell population dynamics with different phenotypes. Both the Markovian branching process model (stochastic model) and the ordinary differential equation (ODE) s…

q-bio.CB2013★ 48 cited

A multi-phenotypic cancer model with cell plasticity

Da Zhou, Yue Wang, Bin Wu

The conventional cancer stem cell (CSC) theory indicates a hierarchy of CSCs and non-stem cancer cells (NSCCs), that is, CSCs can differentiate into NSCCs but not vice versa. Howev…

q-bio.PE2011★ 34 cited

Fixation, transient landscape and diffusion's dilemma in stochastic evolutionary game dynamics

Da Zhou, Hong Qian

Agent-based stochastic models for finite populations have recently received much attention in the game theory of evolutionary dynamics. Both the ultimate fixation and the pre-fixat…