9 citations · 21 across the 5 of their papers we have counts for
3 papers · 1 filter
Eukaryotic gene regulation at equilibrium, or non?
Benjamin Zoller, Thomas Gregor, Gašper Tkačik
Models of transcriptional regulation that assume equilibrium binding of transcription factors have been very successful at predicting gene expression from sequence in bacteria. How…
Transcription-dependent spatial organization of a gene locus
Lev Barinov, Sergey Ryabichko, William Bialek +1
There is growing appreciation that gene function is connected to the dynamic structure of the chromosome. Here we explore the interplay between three-dimensional structure and tran…
Precise spatial scaling in the early fly embryo
Victoria Antonetti, William Bialek, Thomas Gregor +3
The early fly embryo offers a relatively pure version of the problem of spatial scaling in biological pattern formation. Within three hours, a "blueprint" for the final segmented b…