4 papers
Writhe-Based Polymer Link Classification Using Machine Learning
Jack Beda, Djordje Mihajlovic, Kasturi Barkataki +1
Unique and rapid classification of knots and links is an open mathematical problem that is relevant to a range of (bio)physical systems, including polymer melts, DNA, and proteins.…
The Integration Host Factor is a pH-responsive protein that switches from DNA bending to DNA bridging in acidic biofilm-like conditions
Dinesh Parthasarathy, Saminathan Ramakrishnan, Georgia Tsang +9
The Integration Host Factor (IHF) is a nucleoid-associated protein critical for both DNA compaction and biofilm stability. While its role in DNA packaging within the cell is well u…
Shortcut learning in geometric knot classification
Djordje Mihajlovic, Davide Michieletto
Classifying the topology of closed curves is a central problem in low dimensional topology with applications beyond mathematics spanning protein folding, polymer physics and even m…
Link to Densify: Topological Transitions and Origin of Hysteresis During the (De)Compression of Amorphous Ices
Yair Augusto Gutiérrez Fosado, Davide Michieletto, Fausto Martelli
In this Letter we study the phase transition between amorphous ices and the nature of the hysteresis cycle separating them. We discover that a topological transition takes place as…