301 citations · 2.5k across the 73 of their papers we have counts for
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Unfolding knots by proteasome-like systems: simulations of the behaviour of folded and neurotoxic proteins
Michał Wojciechowski, Àngel Gómez-Sicilia, Mariano Carrión-Vázquez +1
Knots in proteins have been proposed to resist proteasomal degradation. Ample evidence associates proteasomal degradation with neurodegeneration. One interesting possibility is tha…
Stiffness of the C-terminal disordered linker affects the geometry of the active site in endoglucanase Cel8A
Bartosz Rozycki, Marek Cieplak
Cellulosomes are complex multi-enzyme machineries which efficiently degrade plant cell-wall polysaccharides. The multiple domains of the cellulosome proteins are often tethered tog…
Criteria for folding in structure-based models of proteins
Karol Wołek, Marek Cieplak
In structure-based models of proteins, one often assumes that folding is accomplished when all contacts are established. This assumption may frequently lead to a conceptual problem…