10 papers
A stability-preserving polytopal discontinuous Galerkin method for the Fisher-Kolmogorov model with applications to neurodegenerative disease modelling
Paola Francesca Antonietti, Francesca Bonizzoni, Mattia Corti +3
The Fisher--Kolmogorov equation models the spatio-temporal evolution of interacting biological species and is extensively employed in fields such as ecology, population dynamics, a…
The functional impact of myofiber macroscopic organization and disarray in computational models of the murine heart
Carlo Guastamacchia, Roberto Piersanti, Francesco Giardini +5
A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation ar…
The internal law of a material can be discovered from its boundary
Francesco Regazzoni
Since the earliest stages of human civilization, advances in technology have been tightly linked to our ability to understand and predict the mechanical behavior of materials. In r…
Elimination-compensation pruning for fully-connected neural networks
Enrico Ballini, Luca Muscarnera, Alessio Fumagalli +2
The unmatched ability of Deep Neural Networks in capturing complex patterns in large and noisy datasets is often associated with their large hypothesis space, and consequently to t…
Shape-informed cardiac mechanics surrogates in data-scarce regimes via geometric encoding and generative augmentation
Davide Carrara, Marc Hirschvogel, Francesca Bonizzoni +3
High-fidelity computational models of cardiac mechanics provide mechanistic insight into the heart function but are computationally prohibitive for routine clinical use. Surrogate…
Cardiocirculatory Computational Models for the Study of Hypertension
Simone Celora, Andrea Tonini, Francesco Regazzoni +3
In this work, we develop patient-specific cardiocirculatory models with the aim of building Digital Twins for hypertension. In particular, in our pathophysiology-based framework, w…