12 papers · 1 filter
A stability-preserving polytopal discontinuous Galerkin method for the Fisher-Kolmogorov model with applications to neurodegenerative disease modelling
Paola Francesca Antonietti, Francesca Bonizzoni, Mattia Corti +3
The Fisher--Kolmogorov equation models the spatio-temporal evolution of interacting biological species and is extensively employed in fields such as ecology, population dynamics, a…
The functional impact of myofiber macroscopic organization and disarray in computational models of the murine heart
Carlo Guastamacchia, Roberto Piersanti, Francesco Giardini +5
A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation ar…
The internal law of a material can be discovered from its boundary
Francesco Regazzoni
Since the earliest stages of human civilization, advances in technology have been tightly linked to our ability to understand and predict the mechanical behavior of materials. In r…
Cardiocirculatory Computational Models for the Study of Hypertension
Simone Celora, Andrea Tonini, Francesco Regazzoni +3
In this work, we develop patient-specific cardiocirculatory models with the aim of building Digital Twins for hypertension. In particular, in our pathophysiology-based framework, w…
Improvements on uncertainty quantification with variational autoencoders
Andrea Tonini, Tan Bui-Thanh, Francesco Regazzoni +2
Inverse problems aim to determine model parameters of a mathematical problem from given observational data. Neural networks can provide an efficient tool to solve these problems. I…
Influence of cellular mechano-calcium feedback in numerical models of cardiac electromechanics
Irena RadiÅ¡iÄ, Francesco Regazzoni, Michele Bucelli +3
Multiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysic…