676 citations · 3.2k across the 68 of their papers we have counts for
8 papers · 1 filter
Confluent and non-confluent phases in a model of cell tissue
Eial Teomy, David A. Kessler, Herbert Levine
The Voronoi-based cellular model is highly successful in describing the motion of two-dimensional confluent cell tissues. In the homogeneous version of this model, the energy of ea…
Collective signal processing in cluster chemotaxis: roles of adaptation, amplification, and co-attraction in collective guidance
Brian A. Camley, Juliane Zimmermann, Herbert Levine +1
Single eukaryotic cells commonly sense and follow chemical gradients, performing chemotaxis. Recent experiments and theories, however, show that even when single cells do not chemo…
Properties of Cooperatively Induced Phases in Sensing Models
Stuart A. Sevier, Herbert Levine
A large number of eukaryotic cells are able to directly detect external chemical gradients with great accuracy and the ultimate limit to their sensitivity has been a topic of debat…
Periodic migration in a physical model of cells on micropatterns
Brian A. Camley, Yanxiang Zhao, Bo Li +2
We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micropatterned substrates. This model couples cell morphology, adhesion, and cy…
Self-assisted Amoeboid Navigation in Complex Environments
Inbal Hecht, Herbert Levine, Wouter-Jan Rappel +1
Background: Living cells of many types need to move in response to external stimuli in order to accomplish their functional tasks; these tasks range from wound healing to immune re…
Determining the accuracy of spatial gradient sensing using statistical mechanics
Bo Hu, Wen Chen, Wouter-Jan Rappel +1
Many eukaryotic cells are able to sense chemical gradients by directly measuring spatial concentration differences. The precision of such gradient sensing is limited by fluctuation…
Coexistence of amplitude and frequency modulations in intracellular calcium dynamics
Maurizio De Pitta, Vladislav Volman, Herbert Levine +3
The complex dynamics of intracellular calcium regulates cellular responses to information encoded in extracellular signals. Here, we study the encoding of these external signals in…
Physical Schemata Underlying Biological Pattern Formation - Examples, Issues and Strategies
Herbert Levine, Eshel Ben-Jacob
Biological systems excel at building spatial structures on scales ranging from nanometers to kilometers and exhibit temporal patterning from milliseconds to years. One approach tha…