206 citations · 248 across the 5 of their papers we have counts for
4 papers · 1 filter
Functional analysis of a gene locus in response to non-canonical combinations of transcription factors
Netta Haroush, Michal Levo, Eric Wieschaus +1
Transcription factor combinations determine gene locus activity and thereby cell identity. However, the precise link between concentrations of such activating transcription factors…
Trading bits in the readout from a genetic network
Marianne Bauer, Mariela D. Petkova, Thomas Gregor +2
In genetic networks, information of relevance to the organism is represented by the concentrations of transcription factor molecules. In order to extract this information the cell…
Optimal decoding of information from a genetic network
Mariela D. Petkova, Gašper Tkačik, William Bialek +2
Gene expression levels carry information about signals that have functional significance for the organism. Using the gap gene network in the fruit fly embryo as an example, we show…
Positional information, in bits
Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus +2
Cells in a developing embryo have no direct way of "measuring" their physical position. Through a variety of processes, however, the expression levels of multiple genes come to be…