activity
20112023
most citedOptimal decoding of information from a genetic network

206 citations · 248 across the 5 of their papers we have counts for

collaborators

5 papers

q-bio.MN2023

Functional analysis of a gene locus in response to non-canonical combinations of transcription factors

Netta Haroush, Michal Levo, Eric Wieschaus +1

Transcription factor combinations determine gene locus activity and thereby cell identity. However, the precise link between concentrations of such activating transcription factors…

q-bio.MN2020★ 33 cited

Trading bits in the readout from a genetic network

Marianne Bauer, Mariela D. Petkova, Thomas Gregor +2

In genetic networks, information of relevance to the organism is represented by the concentrations of transcription factor molecules. In order to extract this information the cell…

q-bio.TO2017★ 5 cited

Quantification of myosin distribution predicts global morphogenetic flow in the fly embryo

Sebastian J Streichan, Matthew F Lefebvre, Nicholas Noll +2

During embryogenesis tissue layers continuously rearrange and fold into specific shapes. Developmental biology identified patterns of gene expression and cytoskeletal regulation un…

q-bio.MN2016★ 206 cited

Optimal decoding of information from a genetic network

Mariela D. Petkova, Gašper Tkačik, William Bialek +2

Gene expression levels carry information about signals that have functional significance for the organism. Using the gap gene network in the fruit fly embryo as an example, we show…

q-bio.MN2011★ 4 cited

Positional information, in bits

Julien O. Dubuis, Gasper Tkacik, Eric F. Wieschaus +2

Cells in a developing embryo have no direct way of "measuring" their physical position. Through a variety of processes, however, the expression levels of multiple genes come to be…