171 citations · 630 across the 10 of their papers we have counts for
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q-bio.PE2020
Tregs self-organize into a "computing ecosystem" and implement a sophisticated optimization algorithm for mediating immune response
Robert Marsland, Owen Howell, Andreas Mayer +1
Regulatory T cells (Tregs) play a crucial role in mediating immune response. Yet an algorithmic understanding of the role of Tregs in adaptive immunity remains lacking. Here, we pr…
q-bio.PE2020★ 58 cited
Early life imprints the hierarchy of T cell clone sizes
Mario U. Gaimann, Maximilian Nguyen, Jonathan Desponds +1
The adaptive immune system responds to pathogens by selecting clones of cells with specific receptors. While clonal selection in response to particular antigens has been studied in…