246 citations · 384 across the 27 of their papers we have counts for
4 papers · 1 filter
Online control of the false discovery rate in biomedical research
David S. Robertson, James M. S. Wason
Modern biomedical research frequently involves testing multiple related hypotheses, while maintaining control over a suitable error rate. In many applications the false discovery r…
Blinded and unblinded sample size re-estimation in crossover trials balanced for period
Michael Grayling, Adrian Mander, James Wason
The determination of the sample size required by a crossover trial typically depends on the specification of one or more variance components. Uncertainty about the value of these p…
Design optimisation and post-trial analysis in group sequential stepped-wedge cluster randomised trials
Michael Grayling, David Robertson, James Wason +1
Recently, methodology was presented to facilitate the incorporation of interim analyses in stepped-wedge (SW) cluster randomised trials (CRTs). Here, we extend this previous discus…
Familywise error control in multi-armed response-adaptive trials
David S. Robertson, James M. S. Wason
Response-adaptive designs allow the randomization probabilities to change during the course of a trial based on cumulated response data, so that a greater proportion of patients ca…